moderate depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Aged range 18-50 years, male or female, right handed; (2) Met the diagnosis criteria of depressive disorder according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5); (3) Hamilton Depression Scale (HAMD-24) score is 27-35 (Moderate depression); (4) No medical treatment, physical and psychological therapy more than 3 weeks or maintain stable medical treatment at least 3 weeks; (5) People who volunteer to participate in this study and sign the written informed consent.
Exclusion criteria
Exclusion criteria: (1) History of self harm or suicide; (2) History of schizophrenia, bipolar disorder or severe personality disorder; (3) History of alcohol abuse or drug dependence; (4) History of severe traumatic brain injury or epilepsy; (5) Participants who have serious cardiovascular diseases, liver diseases or kidney diseases; (6) People who refuse acupuncture treatment during the trial; (7) Metal implant in skull or pacemaker; (8) Women in pregnant or lactating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD-24; | — |
Secondary
| Measure | Time frame |
|---|---|
| BDI;Motor evoked potentials (MEPs);The resting motor threshold (rMT);Contralateral silent period (CSP);Rating Scale for Side Effects (SERS); | — |
Countries
China