Clinical observation of flurbiprofen axetil combined with dexmedetomidine in the treatment of pain after burn skin grafting

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000029897

Enrollment

Unknown

Registered

2020-02-16

Start date

2020-03-01

Completion date

Unknown

Last updated

2020-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burn pain

Interventions

control group:flurbiprofen axetil

experimental group:flurbiprofen axetil combined with dexmedetomidine

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. From 18 to 60 years of age; 2. Patients with third degree burn who have clear indication of operation and agree to skin grafting; 3. There was no contraindication before operation.

Exclusion criteria

Exclusion criteria: 1. Known or suspected allergies to a-2 receptor agonists or nonsteroidal anti-inflammatory drugs; 2.Chronic respiratory dysfunction with sinus bradycardia; 3. Impaired renal or liver function; 4. Regular use of sedatives or antidepressants; 5. Other respiratory burns and/or severe complex injuries; 6. Poor compliance.

Design outcomes

Primary

Measure	Time frame
visual analogue scale;	—

Secondary

Measure	Time frame
ramsay score;Number of times Dizosin was given ;	—

Countries

China

Contacts

Public ContactXu Gang

Department of Burn and Plastic Surgery, North District branch of Subei people's Hospital

xugun2004@126.com+86 18051081692

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026