Migraine
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. To be diagnosed as MWoA; 2. To be considered as the liver depression of the heat syndrome according to liver depression of the heat syndrome diagnosis scale; 3. Aged between 18–50 years and right-handed; 4. Had at least six months of migraine duration; 5. Had not taken any prophylactic medicine during the last three months; 6. Not participating other ongoing clinical studies; 7. Written informed consent was signed.
Exclusion criteria
Exclusion criteria: 1. Be alcohol or drug abusers; 2. Be pregnant or during lactation; 3. Suffered from psychiatric, neurologic, cardiovascular, respiratory or renal illnesses; 4. Suffered from any other chronic pain conditions or had a history of head trauma, with loss of consciousness; 5. Have MRI contraindications, such as claustrophobia; 6. Unable to complete headache diary due to cognitive decline; 7. Be allergic to Chinese medicine herbs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| functional connectivity of salience network; | — |
Secondary
| Measure | Time frame |
|---|---|
| the proportion of responders;the changes of liver depression of the heat syndrome;VAS;MSQ;??????(Self-Rating Depression Scale, SDS);Self-Rating Anxiety, SAS; | — |
Countries
China
Contacts
Beijing Hospital of traditional Chinese Medicine Affiliated to Capital Medical University