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The modulation effect of Qing-Gan Jie-Yu Herbal Formula Granule in Salience Network for migraine patients with liver depression of the heat syndrome: a brain imaging study

The modulation effect of Qing-Gan Jie-Yu Herbal Formula Granule in Salience Network for migraine patients with liver depression of the heat syndrome: a brain imaging study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000029871
Enrollment
Unknown
Registered
2020-02-16
Start date
2020-05-01
Completion date
Unknown
Last updated
2020-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine

Interventions

Sponsors

Beijing Hospital of traditional Chinese Medicine Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. To be diagnosed as MWoA; 2. To be considered as the liver depression of the heat syndrome according to liver depression of the heat syndrome diagnosis scale; 3. Aged between 18–50 years and right-handed; 4. Had at least six months of migraine duration; 5. Had not taken any prophylactic medicine during the last three months; 6. Not participating other ongoing clinical studies; 7. Written informed consent was signed.

Exclusion criteria

Exclusion criteria: 1. Be alcohol or drug abusers; 2. Be pregnant or during lactation; 3. Suffered from psychiatric, neurologic, cardiovascular, respiratory or renal illnesses; 4. Suffered from any other chronic pain conditions or had a history of head trauma, with loss of consciousness; 5. Have MRI contraindications, such as claustrophobia; 6. Unable to complete headache diary due to cognitive decline; 7. Be allergic to Chinese medicine herbs.

Design outcomes

Primary

MeasureTime frame
functional connectivity of salience network;

Secondary

MeasureTime frame
the proportion of responders;the changes of liver depression of the heat syndrome;VAS;MSQ;??????(Self-Rating Depression Scale, SDS);Self-Rating Anxiety, SAS;

Countries

China

Contacts

Public ContactFang Han

Beijing Hospital of traditional Chinese Medicine Affiliated to Capital Medical University

1989hanfang@sina.com+86 15652386453

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026