functional dyspepsia
Conditions
Interventions
placebo group/tandospirone group:tandospirone versus placebo
Sponsors
the First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients meeting the Rome III FD criteria were eligible for enrollment. Included participants were age 18-70 years, had a score of 7-29 for HAMA, PPI or gastrointestinal motility treatment was invalid for at least 4 weeks.
Exclusion criteria
Exclusion criteria: Patients excluded from the study were those who suspected psychological diseases or with severe hepatic or renal dysfunction; patients who had been administered the drugs within 1 week (aspirin, hormonal drugs, prokinetics, acid suppression drug, prostaglandin and non-steroidal anti-inflammatory drugs) or within 4 weeks (anti-anxiety or tranquilizers) before the study were also excluded. Finally, any patients who were pregnant, lactating or attempting to conceive were excluded, as well as patients who were regarded as not being suitable participants by the study investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IL-6;IL-1beta;TNF-alpha;IL-4;IL-10;Brain-derived neurotrophic factor, BDNF; | — |
Secondary
| Measure | Time frame |
|---|---|
| GIS scores;HAMA scores; | — |
Countries
China
Contacts
Public ContactGu Sai
the First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed