The effect of midazolam on dexamethasone-induced perineal pruritus

The effect of midazolam on dexamethasone sodium phosphate injection-induced perineal pruritus

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000029844

Enrollment

Unknown

Registered

2020-02-15

Start date

2020-02-16

Completion date

Unknown

Last updated

2020-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

perineal pruritus

Interventions

experimental group:Before anesthesia induction, received intravenous injection of 0.03mg·kg-1(1mg·ml-1) midazolam

control group:intravenous normal saline of the same volume

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Nighty patients scheduled for selective surgery, aged 18-65years, ASA physical status I~II, BMI 18~30kg·m-2.

Exclusion criteria

Exclusion criteria: Patients with diabetes, paresthesia, allergy to narcotic drugs, routine preoperative use of narcotic analgesics, long-term use of hormones, drug and alcohol abuse, communication disorders with mental illness, pregnancy or lactation, and severe systemic illness and reluctance to undergo this study.

Design outcomes

Primary

Measure	Time frame
VAS scores;duration of itching;	—

Secondary

Measure	Time frame
Ramsay scores;	—

Countries

China

Contacts

Public ContactLiu Meiyu

Affiliated Hospital of Yangzhou University

myliu@yzu.edu.cn+86 17761980727

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026