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Cancelled by the investigator Clinical Study of Cord Blood NK Cells Combined with Cord Blood Mesenchymal Stem Cells in the Treatment of Acute Novel Coronavirus Pneumonia (COVID-19)

Clinical Study of Cord Blood NK Cells Combined with Cord Blood Mesenchymal Stem Cells in the Treatment of Acute Novel Coronavirus Pneumonia (COVID-19)

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000029817
Enrollment
Unknown
Registered
2020-02-14
Start date
2020-02-20
Completion date
Unknown
Last updated
2020-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

novel coronavirus pneumonia (NCP)

Interventions

High dose group:High-dose NK cells (>5x10^9)and mesenchymal stem cells(>5x10^9),Intravenous infusion once every two days for a total of five times
Conventional dose group:Conventional dose NK cells (>3x10^9)and mesenchymal stem cells(>3x10^9),Intravenous infusion once every two days for a total of three times
Preventive dose group:Preventive dose NK cells (>3x10^9)and mesenchymal stem cells(>3x10^9),Intravenous infusion once every week for a total of one time

Sponsors

Guangzhou reborn health management consultation co., LTD
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with confirmed new coronavirus-infected pneumonia; 2. Voluntarily sign written informed consent.

Exclusion criteria

Exclusion criteria: 1. Extremely ill patients with shock, acute respiratory distress syndrome, and multiple organ failure; 2. Pregnant or lactating women; 3. In the opinion of the investigator, previous or present illnesses may affect patients' participation in the trial or influence the outcome of the study, including: malignant disease, autoimmune disease, liver and kidney disease, blood disease, neurological disease, and endocrine Disease; currently suffering from diseases that seriously affect the immune system, such as: human immunodeficiency virus (HIV) infection, or the blood system, or splenectomy, organ transplantation, etc .; 4. The investigator believes that the patient has other conditions that are not suitable for enrollment.

Design outcomes

Secondary

MeasureTime frame
Time and rate of coronavirus become negative;Clearance rate and time of main symptoms (fever, fatigue, cough);Exacerbation (transfer to RICU) time;Routine blood test;Biochemical Indicators;Immune indices;

Primary

MeasureTime frame
Time to disease recovery;

Contacts

Public ContactChao Xu

Guangzhou reborn health management consultation co., LTD

164972769@qq.com+86 15018720816

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026