arthritis
Conditions
Interventions
control group :NS 100ml i.v. q12h, from 3 days before the operation
experimental group :TXA 1.5g i.v. q12h, from 3 days before the operation
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed as rheumatoid arthritis according to the "Classification of Rheumatoid Arthritis" revised by the American College of Rheumatology in 1978 and the classification of rheumatoid arthritis by the American College of Rheumatology and the European Union of Rheumatology in 2010. Kellgren-LawrenceX line is graded III or IV; 2. Initial unilateral TJA surgery; 3. Perioperative TXA antifibrinolytic therapy.
Exclusion criteria
Exclusion criteria: 1. The patients with severe cardiovascular disease (such as myocardial infarction, atrial fibrillation, angina pectoris, heart failure, etc.), cerebrovascular disease (cerebral infarction, brain Bleeding, etc.; 2. Who need long-term oral anticoagulant drugs (such as aspirin, warfarin, clopidogrel, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood loss; | — |
Secondary
| Measure | Time frame |
|---|---|
| fibrinolysis index;inflammatory index;coagulation indicator ;hemoglobin level;transfusion;range of motion;length of stay;hospitalization expenses ; | — |
Countries
China
Contacts
Public ContactWei Huang
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed