Chronic rhino-sinusitis
Conditions
Interventions
Two groups:high swelling and degradable hemostatic materials versus Control
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years old; 2. The Lund Mackay score of single / bilateral chronic rhinosinusitis patients with or without nasal polyps was more than 2; 3. For the patients who need ess, the operation site is the first operation; 4. The blood coagulation function was normal before operation, and the platelet, Pt and APTT were within the normal value of hospital or judged by the researcher as abnormal without clinical significance; 5. Those who did not participate in other clinical trials within three months before the start of this trial; 6. Voluntarily participate in and sign the informed consent after obtaining full knowledge. Note: for patients with bilateral nasal cavity, use the same packing material on both sides, and randomly select one side as the observation side.
Exclusion criteria
Exclusion criteria: 1. Fungal sinusitis, allergic fungal sinusitis and tumor of nasal cavity and paranasal sinuses; 2. Patients who had used drugs affecting coagulation 2 weeks before operation; patients who had used hormone continuously in the past month, and patients who had used immunosuppressant for a long time; 3. Having mental illness or mental disorder; 4. Patients with surgical contraindications; 5. Pregnant women, lactating women, women of childbearing age who had positive urine HCG 48 hours before the test; male and female subjects did not take effective contraceptive measures, or planned to receive (give) pregnancy within 3 months after the start of the test; 6. Other patients who do not meet the inclusion criteria determined by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative success rate of hemostasis; | — |
Secondary
| Measure | Time frame |
|---|---|
| SNOT-20 at 1 week, 2 week and 4 week postoperation; | — |
Countries
China
Contacts
Public ContactShixi Liu; Feng Liu
West China Hospital, Sichuan University
Outcome results
None listed