Effect of gender differences on dexmedetomidine for sedation in upper limb surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000029783

Enrollment

Unknown

Registered

2020-02-13

Start date

2020-03-01

Completion date

Unknown

Last updated

2020-12-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

upper limb surgery

Interventions

Male group:Intravenous infusion of dexmedetomidine

Female group:Intravenous infusion of dexmedetomidine

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients with brachial plexus block; 2. Aged 20 - 60 years; 3. BMI 18 - 30kg/m2; 4. ASA class I, or II.

Exclusion criteria

Exclusion criteria: 1. Patients with previous surgery; 2. Imperfect brachial plexus block; 3. History of heart, lung, liver, and kidney disease; 4. History of mental and neurological disease; 5. Coagulopathy; 6. History of drug or alcohol abuse; 7. Pregnancy; 8. Allergic to dexmedetomidine; 9. Patients who have recently taken antipsychotics.

Design outcomes

Primary

Measure	Time frame
Observer's Assessment of Alertness/Sedation Scale (OAA/S);Bispectral index (BIS);	—

Secondary

Measure	Time frame
Self-Rating Anxiety Scale (SAS);	—

Countries

China

Contacts

Public ContactLi Juan

The First Affiliated Hospital of University of Science and Technology of China

huamuzi1999@126.com+86 13956005465

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026