dysfunction of Oddi's sphincter
Conditions
Interventions
Case series:Danshu capsule
Sponsors
Shanghai Tongji Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: All of the criteria must be met: 1. Aged 18-70 years old; 2. Patients who have undergone cholecystectomy but still have abdominal pain; 3. Meet the Rome IV diagnostic standard: (1) Meet the diagnostic criteria of biliary pain*; (2) Elevated ALT or ast or AMA, but not simultaneously; (3) There may be dilatation of bile duct or pancreatic duct; (4) No cholelithiasis or other structural abnormality; *Diagnosis standard of biliary pain: the pain is located in the middle and upper abdomen and / or the right upper abdomen, and meets all the following conditions: (1) The pain gradually increased to a stable level, lasting for 30 minutes or longer; (2) The intermittence period was not equal (not daily); (3) The degree of pain may affect the patient's daily activities or force the emergency treatment; (4) The correlation with defecation was not significant (< 20%); (5) There was no significant reduction in pain by changing body position or inhibiting acid treatment (< 20%); 4. Routine blood test, biochemical test (including liver enzyme and pancreatin), abdominal ultrasound and CT after fat meal were performed to eliminate organic diseases; 5. Sign the informed consent voluntarily.
Exclusion criteria
Exclusion criteria: 1. Abdominal pain is caused by organic diseases, such as stone, pancreatitis, pancreatic tumor and liver disease; 2. Diabetes mellitus and thyroid function disease; 3. In patients with severe heart, lung, central nervous system, liver, gallbladder and pancreatic organic diseases, the active phase of liver disease or liver function is abnormal, ALT or AST is more than 2 times the upper limit of normal value; in patients with renal disease or renal insufficiency, SCR is more than 1.3 times the upper limit of normal value; in patients with pancreatitis, amylase and lipase are more than 3 times the upper limit of normal value; Lactation, pregnancy or planned pregnancy women; 4. Those who have participated in or are participating in other clinical trials in the past 3 months; 5. Patients who the researchers think can not be included in the group.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pain questionnaire; | — |
Secondary
| Measure | Time frame |
|---|---|
| B-ultrasound;blood; | — |
Countries
China
Contacts
Public ContactChangqing Yang
Shanghai Tongji University
Outcome results
None listed