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The application of conventional ultrasound combined with contrast-enhanced ultrasound in the differential diagnosis of subpleural pulmonary nodule

The application of conventional ultrasound combined with contrast-enhanced ultrasound in the differential diagnosis of subpleural pulmonary nodule

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000029749
Enrollment
Unknown
Registered
2020-02-12
Start date
2020-04-01
Completion date
Unknown
Last updated
2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subpleural pulmonary nodule

Interventions

Gold Standard:Pathologic Diagnosis
ultrasound&#32
combined&#32
with&#32
contrast-enhanced&#32
ultrasound

Sponsors

Shanghai Pulmonary Hospital affiliated to Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The lesion could be localized beneath the pleura by imaging examination; 2. The lesion was diagnosed by pathological, etiological examination or diagnostic therapy; 3. US images of the lesion were clear and could be preserved in whole.

Exclusion criteria

Exclusion criteria: 1. US images of the lesion were unclear due to the interference of gas, bones or other causes; 2. High risk of hypersensitivity to UCA; 3. Severe cardiovascular disease, liver or kidney dysfunction, mental disorders, etc.; 4. Disagreement to participate in this trial; 5. Other conditions that might affect the study.

Design outcomes

Primary

MeasureTime frame
Lesion morphology;Time difference between lesion and lung;Chest wall and lesion;The proportion of time;Initial enhancement and time of lesions;

Secondary

MeasureTime frame
half-time of lesion intensity reduction, intensity of 60s, 120s and 180s;initial enhancement and time of chest wall;initial enhancement and time of chest wall;Characteristics of necrotic areas;Characteristics of necrotic areas;

Countries

China

Contacts

Public ContactWang Yin

Shanghai Pulmonary Hospital affiliated to Tongji University

lpbbl@aliyun.com+86 13701885138

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 14, 2026