Laparoscopic Liver Resection
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The patients who plan to undergo laparoscopic liver resection with low central venous pressure. 2. ASA grades is I~II. 3. Child grads is A. 4. The patients age range from 18 to 74 years.
Exclusion criteria
Exclusion criteria: 1. The operation method changes during the procedure: transfer laparotomy; 2. There is a intra-operative sustained hemorrhage, CLCVP technique can not be performed, or can not keep the blood pressure maintained by a single test vasoconstrictor; 3. There exists any Cardio-cerebrovascular disease: cardiac function grades III~IV, echocardiographic indicates LEVF< 50% or patients with moderate and severe valve regurgitation and preoperative arrhythmia; Severe cerebrovascular disease, peripheral vascular disease, uncontrolled hypertension; 4. Abnormal liver and kidney function; 5. The patient who is allergic to the test drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the frequency of cardiovascular adverse events;eGFR;BUN; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure;Cardiac index;The pH value of arterial blood;Lactic acid value;SVV; | — |
Countries
China
Contacts
The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China