Frailty
Conditions
Interventions
Cohort 2:No Frailty
Sponsors
The First Affiliated Hospital of College of Medicine of Zhejiang University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged 65 years or above; 2. ASA class I-III; 3. Inpatients who planned to have an elective gastrointestinal endoscopy under general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications for routine endoscopic procedures or patients who refuse anesthesia; 2. Patients who require endotracheal intubation; 3. Anesthesia is administered for less than 30 minutes or more than 90 minutes; 4. Patients with uncontrolled, potentially life-threatening circulatory and(or) respiratory diseases; and(or) severe liver dysfunction (Child-Pugh C), and(or) severe renal dysfunction, and(or) acute upper gastrointestinal hemorrhage with shock, and(or) severe anemia, and(or) gastrointestinal obstruction with gastric content retention; 5. Patients without escort or guardian; 6. Allergic to narcotic drugs, opioids or other anesthesia-related drugs; 7. Patients with difficult airway; 8. Patients with severe neurological or psychiatric disorders; 9. Substance abuser; 10. Patients with morbid obesity; 11. Patients with high risk of anesthesia; 12. The disabled.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Aldrete Score;Modified Post Anesthetic Discharge Scoring System scale;Sensitivity;Specificity;False positive rate;False negative rate;Accuracy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Awakening time;Numerical Rating Scale;Complications;Dosage of propofol;Vital signs; | — |
Countries
China
Contacts
Public ContactFang Xiangming
Department of Anesthesiology, The First Affiliated Hospital of College of Medicine of Zhejiang University
Outcome results
None listed