End-stage Renal Disease
Conditions
Interventions
Group 1:Total intraveous anesthesia
Group 2:Sevoflurane inhalation anesthesia
Sponsors
Department of Anesthesiology and Perioperative Medicine, the Second Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with renal secondary hyperparathyroidism scheduled for parathyroidectomy + auto-transplantation; 2. American Society Association physical status 2-3; 3. Aged 18-65 years old.
Exclusion criteria
Exclusion criteria: 1. History of severe respiratory, central nervous system or hepatic disease; 2. Cardiac function worse than grade 3 or cardiac ejection fraction <40%; 3. Known family history of malignant hyperthermia; 4. Acid-base or electrolyte abnormalities; 5. Contraindication to inhalational anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cardiac output;stroke volume;comsumption of dopamine;systemic vascular resistance;stroke volume variation; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressure;heart rate;bispectral index;duration of surgery;duration of anesthesia;length of awake time;intensity of pain (numeric rate score);adverse event;parathyroidectomy assessment of symptoms score;hyperparathyroidism recurrenc after surgery;arterial bloos gas analysis;health-related quality of life; | — |
Countries
China
Contacts
Public ContactYun Wu
Department of Anesthesiology and Perioperative Medicine, the Second Affiliated Hospital of Anhui Medical University
Outcome results
None listed