Nasal polyp
Conditions
Interventions
the nasal polypectomy group:cis atracurium
the nasal polypectomy group:vecuronium bromide
the nasal polypectomy group:rocuronium bromide
the nasal septum correction group:cis atracurium
the nasal septum correction group:vecuronium bromide
the nasal septum correction group:rocuronium bromide
Sponsors
The first Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients with American Society of Anesthesiologists(ASA)physical status I-II,aged18–65years, scheduled for nasal polypectomy and nasal septum correction; 2. All patients had no liver or kidney disease, no neuromuscular disorders, and no acid-base and electrolyte disorders. Histamine receptor agonists or antagonists, and drugs that are known to affect neuromuscular transmissionwere were not used preoperatively.
Exclusion criteria
Exclusion criteria: 1. Poor general condition; 2. With cardiovascular diseases and chronic obstructive pulmonary disease; 3. Severe atherosclerosis; 4. Severe hepatorenal dysfunction; 5. Acid-base and electrolyte disorders; 6. Perioperative hemodynamic instability (the intraoperative blood loss was more than 800 ml); 7. A history of serious hypersensitivity to the drugs or food.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| histamine; | — |
Secondary
| Measure | Time frame |
|---|---|
| the histamine receptor;Haemodynamic variables monitored;The neuromuscular blocking effect; | — |
Countries
China
Contacts
Public ContactYanning Qian
Department of Anesthesiology, The first Affiliated Hospital of Nanjing Medical University
Outcome results
None listed