Characteristic of Intestinal Flora of Patients with Depression in Chengdu, Sichuan Province and Its Relevance with Metabolism and Efficacy of Therapeutic for Depression

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000029703

Enrollment

Unknown

Registered

2020-02-09

Start date

2020-02-15

Completion date

Unknown

Last updated

2020-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

case series:SSRIs

control group:no intervention

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. meet the Diagnostic criteria of depression: DSM-5 (); 2. the main residence is in Chengdu Basin without long-term (more than 2 weeks) history of living in other places in the past one year; 3. never taken any antipsychotic or antidepressant drugs; 4. never taken antibiotics in the past one month; 5. aged 18 to 45 years old; 6. volunteer to participate in the study and sign a written informed consent.

Exclusion criteria

Exclusion criteria: 1. suffering from serious physical disease (especially metabolic diseases affecting intestinal flora), substance dependency and nervous system diseases; 2. suffering from other mental diseases; 3. suffering from condition affecting psychological assessment and testing, for example, color blindness, color weakness, deafness, stuttering, etc.

Design outcomes

Primary

Measure	Time frame
intestinal flora;metabolites of flora;drug metabolism;HAMD index;	—

Countries

China

Contacts

Public ContactZaiquan Dong

West China Hospital of Sichuan University

zaiquan_dong@163.com+86 13032881127

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 22, 2026