Satiety Response
Conditions
Interventions
four groups :Ingested 4 different samples
Sponsors
Beijing Research Institute for Nutritional Resources
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Males or female aged 18-60 years old; 2. BMI 18.5 to 28kg/m2 (Normal weight group with BMI between 18.5 to 24 and Over-weight group with BMI between 24 to 28); 3. Healthy and taking no regular medications other than birth control or hormone replacement therapy. Testing in women should be controlled for menstrual phase (i.e. follicular); Able to provide informed consent and authorize release of relevant health information; No serious liver, kidney, digestive tract diseases and metabolic diseases such as diabetes as checked by medical examination; No blood lipid-related drugs used within 3 months, and agreed not to use drugs during the experiment; Willing and able to sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Women who are pregnant or nursing; 2. Gain or loss of > 4kg in the last 3 months; 3. Taking the prescription or over the counter weight loss medications or weight loss supplements; 4. Use of an investigational drug product within 30 days prior to the study period; 5. Extreme dietary habits (e.g. Zone diet or Atkins diet); 6. Dietary restraint on the Three Factor Eating Questionnaire score > 14; 7. Surgery or hospitalization in last 3 months; 8. History of severe or significant gastrointestinal disorder; 9. History of eating disorder (binge eating, anorexia, bulimia nervosa, etc.); 10. Diabetes mellitus (fasting glucose >126 mg/dL); 11. Allergy or reported GI intolerance to any of the foods used for the test meals; 12. Combining serious diseases such as heart, liver, kidney, gastrointestinal disorder and hematopoietic system, mentally ill patients; 13. Allergic or reported GI intolerance to any of the foods used for the test meals; 14. Prescription or over the counter weight loss medications / weight loss supplements; 15. Taking an investigational drug product within 30 days prior to the study period; 16. Excessive smoking or alcohol consumption (<15 cigarettes/d, <25g/d alcohol for men, or <15g/d alcohol/d for women); 17. Not intaking the samples according to the regulations, or things that affected the efficacy of or safety judgement, situations or uncompleted data judged by the PI that affected the trail 18. Not participation in any clinical trial within the past 30 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glycemic index;Insulin Index;Satiety score; | — |
Countries
China
Contacts
Public ContactJingyi Chang
Beijing Research Institute for Nutritional Resources
Outcome results
None listed