Proliferative diabetic retinopathy
Conditions
Interventions
Gold Standard:According to the International Clinical DR Severity Classification Standards developed by the American Academy of Ophthalmology in 2002, fundus examination meets the PDR classification a
Index test:CircRNA 
expression 
in 
vitreous.
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for PDR; 2. PDR with tractional retinal detachment or continuous non-absorption of vitreous hemorrhage requires PPV surgery; 3. Patients with not received PPV surgery before.
Exclusion criteria
Exclusion criteria: 1. Patients with severe proliferative vitreoretinopathy and need loosen the retina; 2. Patients with large-scale traction retinal detachment; 3. Patients with macular holes before or during surgery; 4. Patients with other serious eye diseases besides PDR, such as uveitis, endophthalmitis, etc.; 5. Patients with contraindications to PPV surgery, such as severe hypertension, abnormal liver or kidney function, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| best corrected visual acuity;central foveal thickness;postoperative vitreous hemorrhage;circRNA in vitreous; | — |
Countries
China
Contacts
Public ContactQinghua Qiu
Shanghai General Hospital
Outcome results
None listed