H. pylori infection eradication
Conditions
Interventions
Control group:Standard bismuth quadruple therapy
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged> 60 years; 2. Hp-positive patients who need Hp eradication treatment; 3. The pathological results of gastric mucosa biopsy suggest a positive result, or a 13-carbon urea breath test; 4. No previous Hp eradication treatment; 5. Voluntarily participate and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1) refuse to join the group; 2) The standard H. pylori eradication treatment has been performed before enrollment; 3) Those who have used antibiotics, bismuth before 4 weeks of treatment or H2RA and PPI before 2 weeks of treatment; 4) Gastric examination reveals gastric cancer; 5) Severe drinking (the daily alcohol intake exceeds 50G for more than 6 months); 6) Patients with severe primary diseases of liver, kidney, heart, brain, lung, endocrine system and hematopoietic system cannot be effectively controlled; 7) Clinically significant liver and kidney dysfunction (transaminase is greater than 1.5 times the upper limit of normal value, or blood creatinine is greater than the upper limit of normal value) or liver disease, anemia (hemoglobin <90g/L); 8) Those who are allergic to the drugs used in this research;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Carbon 13 expiratory value; | — |
Countries
China
Contacts
Public ContactYin Zhu
The First Affiliated Hospital of Nanchang University
Outcome results
None listed