Non-small cell lung cancer, stage I-III
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years; 2. ECOG score 0-1; 3. Patients with stage I-III non-small cell lung cancer confirmed by histopathology or cytology; 4. Staged anti-cancer treatment (including surgery, radiotherapy, chemotherapy, targeted therapy) has been completed; 5. BMI >= 18.5; 6. Expected survival time >= 3 months; 7. Voluntarily participate in this research and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with acute and chronic diseases of the gastrointestinal tract, including acute gastritis, chronic gastritis, peptic ulcer, acute enteritis, chronic enteritis, irritable bowel syndrome, etc; 2. Consumption of citrus foods over 50g/d (fruit juice, orange peel, tangerine peel, grapefruit tea, etc.) in the past week; 3. Complicated with fracture, limb disability, or severe rheumatoid arthritis; 4. Complicated with serious diseases such as heart, liver, kidney and hematopoietic system; 5. With a history of other malignancies (except for cervical carcinoma in situ or basal cell carcinoma of the skin and other malignancies that have been cured for 5 years); 6. Having other serious diseases, including but not limited to: a. Uncontrollable congestive heart failure (NYHA class III or IV), unstable angina pectoris, poorly controlled arrhythmia, uncontrolled hypertension above moderate (SBP> 160mmHg or DBP> 100mmHg); b. Active infection; c. Fasting blood glucose> 7.2mmol/L; d. Mental illnesses that affect informed consent and/or research compliance; 7. Severe allergic constitution; 8. Pregnant or lactating women, women of childbearing age who have not used contraception; 9. Paticipating in other clinical trials or less than 3 months after completion of the previous clinical trial; 10. There are situations that researchers consider inappropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tumor markers;Inflammation markers;Oxidative stress markers;Immunity markers;Metabolite- Perillic acid;Changes of daily activity;Safety indicators; | — |
Countries
China
Contacts
Tongren Hospital, Shanghai Jiaotong University School of Medicine