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Effects for perioperative oral carbohydrate on insulin resistance and postoperative recovery in patients with type 2 diabetes mellitus undergoing coronary artery bypass grafting

Effects for perioperative oral carbohydrate on insulin resistance and postoperative recovery in patients with type 2 diabetes mellitus undergoing coronary artery bypass grafting

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000029664
Enrollment
Unknown
Registered
2020-02-09
Start date
2020-04-01
Completion date
Unknown
Last updated
2020-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease with type 2 diabetes mellitus

Interventions

control group:Fasting for 12 hours before surgery
experimental group:Oral carbonhydrate 355ml 12 hours before surgery

Sponsors

Fuwai Hospital, Chinese Academy of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients scheduled to receive off-pump coronary artery bypass grafting in Fuwai hospital; 2. Patients aged between 18 and 80 years; 3. Patients with type 2 diabetes mellitus; 4. Patients scheduled for the first operation; 5. Patients who agreed to participate in the study and signed informed consent file.

Exclusion criteria

Exclusion criteria: 1. Patients with other cardiovascular diseases or deformities; 2. Patients with gastroesophageal reflux disease; 3. Patients scheduled to receive other operations at the same time or emergency operations.

Design outcomes

Primary

MeasureTime frame
HOMA-ß;

Secondary

MeasureTime frame
Blood glucose;Blood insulin;Blood glucagon;Free fatty acid;HOMA-IR;Interleukin 1;Hypersensitive c-reactive protein;Serum epinephrine;Serum norepinephrine;pH of gastric juice;Gastric fluid volume;Subjective well-being;Exogenous insulin dosage;Vasoactive-inotropic score;Liquid therapeutic dose;

Countries

China

Contacts

Public ContactYuntai Yao
yuntaiyao@126.com+86 13683326213

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026