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Study for the relationship between the level of blood tight junction protein and the damage of blood-brain barrier after cerebral hemorrhage

Study for the relationship between the level of blood tight junction protein and the damage of blood-brain barrier after cerebral hemorrhage

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000029660
Enrollment
Unknown
Registered
2020-02-09
Start date
2020-02-05
Completion date
Unknown
Last updated
2020-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracerebral hemorrhage

Interventions

Sponsors

The First Affiliated Hospital of Baotou Medical College
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. With the approval of the Ethics Committee; 2. In line with the diagnostic criteria for cerebral hemorrhage revised by the Fourth National Conference on cerebrovascular diseases; 3. The first occurrence of cerebral hemorrhage, all patients were examined by CT or MRI when they were admitted to the hospital; 4. The hemorrhage was supratentorial cerebral hemorrhage, not broken into the ventricle and subarachnoid space; 5. The age between 18 and 80 years, informed consent was obtained from the patients.

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1. Patients with serious liver and kidney dysfunction, serious digestive system disease, peripheral vascular embolism disease, autoimmune disease, tumor and blood system disease; 2. Patients who can not complete the project; 3. Patients with poor compliance.

Design outcomes

Primary

MeasureTime frame
Occludin;Claudin-5;Brain edema;Sensitivity;Specificity;SEN, SPE, ACC, AUC of ROC;

Secondary

MeasureTime frame
MMP-9;NIHSS;GCS;

Countries

China

Contacts

Public ContactShuhai Shi

The First Affiliated Hospital of Baotou Medical College

shishuhai100@126.com+86 13311145865

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026