Fulminant type 1 diabetes
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for FT1DM: 1. Occurrence of diabetic ketosis or ketoacidosis soon (approximately 7 days) after the onset of hyperglycemic symptoms (elevation of urinary and/or serum ketone bodies at first visit). 2. Urinary C-peptide excretion 16.0 mmol/L and hemoglobin A1C (HbA1C) level 13.9mmol /L); (2) Ketosis; (3) Acidosis (pH < 7.3, HCO3- < 15 mmoL/L).
Exclusion criteria
Exclusion criteria: 1. Patients with cardiopulmonary and liver and kidney dysfunction; 2. Patients with diseases of the blood system and mental diseases; 3. Patients with poor treatment compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| plasma glucose;hemoglobin A1C;SEN, SPE, ACC, AUC of ROC;threshold of the value of plasma glucose/hemoglobin A1C ratio; | — |
Countries
China
Contacts
Department of Endocrinology and Metabolism, West China Hospital of Sichuan University