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Explore the value of plasma glucose/hemoglobin A1C ratio in differentiating between fulminant type 1 diabetes and diabetic ketoacidosis: a retrospective study based on medical records

Explore the value of plasma glucose/hemoglobin A1C ratio in differentiating between fulminant type 1 diabetes and diabetic ketoacidosis: a retrospective study based on medical records.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000029645
Enrollment
Unknown
Registered
2020-02-09
Start date
2020-02-20
Completion date
Unknown
Last updated
2020-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fulminant type 1 diabetes

Interventions

Gold Standard:Clinical outcomes
Index test:the&#32
value&#32
of&#32
glucose/hemoglobin&#32
A1C&#32

Sponsors

Department of Endocrinology and Metabolism, West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
10 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for FT1DM: 1. Occurrence of diabetic ketosis or ketoacidosis soon (approximately 7 days) after the onset of hyperglycemic symptoms (elevation of urinary and/or serum ketone bodies at first visit). 2. Urinary C-peptide excretion 16.0 mmol/L and hemoglobin A1C (HbA1C) level 13.9mmol /L); (2) Ketosis; (3) Acidosis (pH < 7.3, HCO3- < 15 mmoL/L).

Exclusion criteria

Exclusion criteria: 1. Patients with cardiopulmonary and liver and kidney dysfunction; 2. Patients with diseases of the blood system and mental diseases; 3. Patients with poor treatment compliance.

Design outcomes

Primary

MeasureTime frame
plasma glucose;hemoglobin A1C;SEN, SPE, ACC, AUC of ROC;threshold of the value of plasma glucose/hemoglobin A1C ratio;

Countries

China

Contacts

Public ContactZhang Yuwei

Department of Endocrinology and Metabolism, West China Hospital of Sichuan University

492032132@qq.com+86 18980606700

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026