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Effect of magnesium sulfate on brachial plexus nerve block and the rebound pain after the block disappeared-single center randomized controlled study

Effect of magnesium sulfate on brachial plexus nerve block and the rebound pain after the block disappeared-single center randomized controlled study

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000029640
Enrollment
Unknown
Registered
2020-02-08
Start date
2020-02-15
Completion date
Unknown
Last updated
2020-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Unilateral upper limb injury involving a muscle, joint, or bone

Interventions

control group:10ml 1% Ropivacaine and 10ml Normal Saline.
experimental group:10ml 1% Ropivacaine+2ml 25% Magnesium Sulfate and 10ml Normal Saline.

Sponsors

Department of Anesthesiology, Zhujiang Hospital, Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 60 Years

Inclusion criteria

Inclusion criteria: Undergoing elective orthopedic surgery (relating to the joints, tendons and bones of the shoulder following unilateral upper limb surgery patients), aged 16 to 60, ASA grade I ~ III, body mass index (18 ~ 30 kg/m2), agree to accept PNB treatment, can understand and cooperate with the preoperative and postoperative supervision data acquisition, the patient and family close to the informed consent form and sign of clinical research.

Exclusion criteria

Exclusion criteria: 1) Myocardial injury, cardiac block; 2) Abnormal liver, kidney and lung functions; 3) Gastrointestinal bleeding; 4) Menstruation, lactation women and pregnant women; 5) Hypermagnesemia; 6)Calcium channel blockers for chronic treatment; 7) Contraindications to nerve block (bleeding or coagulation abnormalities, local or systemic infection); 8) chronic pain history or a long history of using sedatives and analgesics; 9)Attending of the history of neuropsychiatric or neuromuscular diseases.

Design outcomes

Primary

MeasureTime frame
Duration of arrest;

Secondary

MeasureTime frame
Sensory block onset time;Motor block onset time;Total analgesics;Sensory recovery time;Motor Recovery time;

Countries

China

Contacts

Public ContactZou Jiaqi

Department of Anesthesiology, Zhujiang Hospital, Southern Medical University

719678209@qq.com+86 15626022208

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026