novel coronavirus pneumonia (COVID-19)
Conditions
Interventions
Case series:Conventional standardized treatment and vMIP atomized inhalation
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) Aged >=18 years, gender unlimited, inpatient; 2) Patients with new coronavirus infection were confirmed: respiratory or blood samples were positive for 2019 ncov nucleic acid by real-time fluorescent RT-PCR, or respiratory or blood samples were highly homologous with known 2019 ncov gene sequencing; 3) According to the standard of "diagnosis and treatment plan for pneumonia with new coronavirus infection (trial version 5)", the clinical types are common type or severe type; 4) The time interval between symptom onset and enrollment was within 7 days. The symptom onset was mainly based on fever. If there was no fever, coughing or other related symptoms could be used, such as fatigue, nasal obstruction, runny nose, chest distress, sore throat, muscle ache, diarrhea, etc; 5) Informed consent has been signed.
Exclusion criteria
Exclusion criteria: 1) Known or suspected to be allergic to the components of vMIP. 2) Confirmed hepatitis B, C, AIDS and other viral infections. 3) Acute respiratory distress syndrome (ARDS) was found. 4) According to the judgment of the researchers, there are other conditions that are not suitable for the experiment. 5) Pregnant, lactating women or during the trial period and within 6 months after the end of the family planning. 6) Have participated in other clinical trials or are using experimental drugs within 12 weeks before administration.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 2019-nCoV nucleic acid turning negative time (from respiratory secretion), or the time to release isolation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clearance rate and time of main symptoms (fever, fatigue, cough);immune indices; | — |
Countries
China
Contacts
Public ContactHu bo, Li wei
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed