Atherosclerotic occlusive disease of the lower extremities
Conditions
Interventions
1:Dual-wire balloon combined with drug-coated ballon
2:simple dual-wire balloon
3:simple drug-coated balloon
Sponsors
Beijing University People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 80 years old; both male and female are adimitted; 2. Diagnosed with femoral-popliteal atherosclerotic occlusive disease, whose cumulative length of lesion is less than 15cm by computed tomogrraphic angiography (CTA). 3. Rutherford category 2-5; 4. Possess operation indication; 5. Treatment and follow-up should be voluntary and a informed consent form would be signed by the patient or legal guardian.
Exclusion criteria
Exclusion criteria: 1. Patients have a paclitaxel allergy or a iodine allergy; 2. Operation contraindications; 3. Patient with current medical condition with a life expectancy less than 3 months; 4. The patient had sympomatic myoinfarction within 3 months or uncontrollable heart failure; 5. The patient had severe respiratory failure (PO2 50 mmHg); 6. The patient had renal failure with creatine level more than 200 umol/L; 7. The patient had severe liver disfunction with alanine aminotransferase level over 3 times.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary patency rate;all-cause mortality;rate of target lesion revascularization; | — |
Secondary
| Measure | Time frame |
|---|---|
| ABI;Rutherford category;late lumen loss; | — |
Countries
China
Contacts
Public ContactZhang Xuemin
Vascular surgery, Beijing University People's Hospital
Outcome results
None listed