Early surgical decompression ameliorates dysfunction of spinal motor neuron in patients with acute traumatic central cord syndrome

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000029562

Enrollment

Unknown

Registered

2020-02-04

Start date

2018-09-01

Completion date

Unknown

Last updated

2020-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute Traumatic Central Cord Syndrome

Interventions

early surgery group:early surgery

late surgery group:late surgery

Eligibility

Sex/Gender

All

Age

20 Years to 85 Years

Inclusion criteria

Inclusion criteria: ATCCS group: (1) With a clear history of trauma; (2) motor impairments in the upper limbs are greater (by at least 10 points in the ASIA motor score) than those in the lower limbs; (3) different degrees of sensory abnormalities with a variable effect on bladder function. Subjects included in the control group: Normal neurologic examinations, including normal muscle strength, sensory function and deep tendon reflexes in the lower extremities.

Exclusion criteria

Exclusion criteria: The exclusion criteria of both subject groups included previous spinal surgery, polyneuropathies, focal neuropathies, peripheral vascular disease, muscle disorders, diabetes, diseases of the central nervous system, syringomyelia, spinal cord tumor/inflammation, and spinal deformities.

Design outcomes

Primary

Measure	Time frame
MUNE;muscle strength;ASIA score;	—

Countries

China

Contacts

Public ContactJiang Jianyuan

Huashan Hospital, Fudan University

countd2388@163.com+86 021 52887130

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026