Cerebrovascular disease
Conditions
Interventions
Sponsors
Department of Neurology, the Affiliated Yantai Yuhuangding Hospital of Qingdao University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2.The time that had elapsed since the patient was last known to be well had to be more than 4.5 hours; 3. Brain MRI showed that lesions on DWI were less than 1/3 of the blood supply area of the middle cerebral artery and there was no obvious signal change in FLAIR; 4. Diagnosis of ischemic stroke, a clear neurological deficit; 5. No previous patients with serious heart disease with ATRIAL fibrillation; 6. Admission NIHSS score < 15 points; 7. Brain CT has ruled out intracranial hemorrhage; 8. Family members signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Aged > 80 years; 2. Previous history of intracranial hemorrhage; 3. Symptoms suggest subarachnoid hemorrhage; 4. Existence of intracranial tumors, arteriovenous malformations or aneurysms; 5. Nearly 3 months have a history of severe head injury or cerebral infarction, but does not include the old small lacunar infarction Symptoms and signs; 6. Nearly a week difficult to oppress the site of hemostasis arterial puncture; 7. Severe liver and kidney dysfunction or severe diabetes; 8. Accompanied by active bleeding; 9. Blood glucose 185 mmHg or diastolic blood pressure> 110 mmHg; 10. Platelet count below normal; oral anticoagulant with INR> 1.7.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NIHSS score;mRS score three months after thrombolysis;symptomatic hemorrhage;Non-symptomatic hemorrhage; | — |
Countries
China
Contacts
Public ContactLiang Zhigang
Department of Neurology, the Affiliated Yantai Yuhuangding Hospital of Qingdao University
Outcome results
None listed