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Effect of aerosolized glucocorticoid on postoperative sore throat after general anesthesia with endotracheal intubation

Effect of aerosolized glucocorticoid on postoperative sore throat after general anesthesia with endotracheal intubation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000029545
Enrollment
Unknown
Registered
2020-02-04
Start date
2020-03-01
Completion date
Unknown
Last updated
2021-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative sore throat

Interventions

experimental group:Budesonide inhalation before anesthesia induction
control group:Normal saline inhalation before anesthesia induction

Sponsors

Shanghai Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. ASA 1-2; 2. Aged 18-80 years; 3. Patients requiring general anesthesia with tracheal intubation.

Exclusion criteria

Exclusion criteria: 1. Proposed airway, maxillofacial and neck surgery and relevant operation history; 2. Recent history of respiratory infection or sore throat; 3. Preoperative evaluation of intubation difficulties (malampati grades III and IV); 4. Poor exposure of intubated laryngeal structures (Cormack Lehane grades III and IV); 5. No less than 3 times of intubation test under direct vision of laryngoscope failed; 6. Cancer, diabetes and other drugs not suitable for glucocorticoids; 7. Oral or nasogastric tube required; 8. No allergy to budesonide or other steroids; 9. Pregnancy.

Design outcomes

Primary

MeasureTime frame
Postoperative sore throat score;

Countries

China

Contacts

Public ContactTian Zijun

Shanghai Sixth People's Hospital

807446313@qq.com+86 13182046798

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026