Study for the efficacy of chloroquine in patients with novel coronavirus pneumonia (COVID-19)

A prospective cohort study for the efficacy and safety of chloroquine in hospitalized patients with novel coronavirus pneumonia (COVID-19)

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000029542

Enrollment

Unknown

Registered

2020-02-03

Start date

2020-02-03

Completion date

Unknown

Last updated

2020-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

novel coronavirus pneumonia (COVID-19)

Interventions

Experimental group:chloroquine

control group:conventional management

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged >=18 years old; 2. Patients has been diagnosed with 2019-nCoV pneumonia according to WHO interim guidance*. * WHO. Clinical management of severe acute respiratory infection when Novel coronavirus (nCoV) infection is suspected: interim guidance. Jan 11, 2020. https://www.who.int/internalpublications-detail/clinical-management-of-severe-acute-respiratoryinfection-when-novel-coronavirus-(ncov)-infection-is-suspected (accessed Jan 29, 2020).

Exclusion criteria

Exclusion criteria: 1. pregnant woman patients; 2. Documented allergic history to chloroquine; 3. Documented history of hematological system diseases; 4. Documented history of chronic liver and kidney diseases; 5. Documented history of cardiac arrhythmia or chronic heart diseases; 6. Documented history of retina or hearing dysfunction; 7. Documented history of mental illnesses; 8. Use of digitalis due to the previous disease.

Design outcomes

Primary

Measure	Time frame
viral negative-transforming time;30-day cause-specific mortality;	—

Secondary

Measure	Time frame
30-day all-cause mortality;SOFA scoring;organ support intensity;total length of hospitalization;length of ICU stay;	—

Countries

China

Contacts

Public ContactJiang Shanping

Sun Yat sen Memorial Hospital of Sun Yat sen University

shanpingjiang@126.com+86 13922738892

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026