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A radiotracer 68Ga-NOTA-PTDGd for PET imaging of tumor hypoxia

68Ga-NOTA-PTDGd for galectin-1 targeted PET imaging of tumor hypoxia

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000029522
Enrollment
Unknown
Registered
2020-02-03
Start date
2020-03-26
Completion date
Unknown
Last updated
2020-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tumor

Interventions

Gold Standard:Pathological examination after surgery, including H & E staining and immunohistochemistry.
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Sponsors

Peking University Health Science Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-70 years; 2. ECGO 0 or 1; 3. Patients with suspected or confirmed lung cancer, esophagus cancer, or cervical cancer who are suggested by the clinicians to conduct PET/CT imaging for tumor diagnosis or staging.

Exclusion criteria

Exclusion criteria: 1. Pregnant or nursing; 2. Severe hepatic or renal dysfunction; 3. Low WBC (less than 3 x 10^9/L); 4. Unable to comply with the PET/CT imaging procedures.

Design outcomes

Primary

MeasureTime frame
SUVmax;SEN, SPE, ACC, AUC of ROC;SEN, SPE, ACC, AUC of ROC;

Countries

China

Contacts

Public ContactZhaofei Liu

Peking University Health Science Center

liuzf@bjmu.edu.cn+86 10 82805825

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 19, 2026