Cervical Cancer
Conditions
Interventions
Pelvic radiotherapy group:Concurrent chemoradiotherapy
Extended field radiotherapy:Concurrent chemoradiotherapy
Sponsors
Guizhou Cancer Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Patients were completely voluntary and autonomous, signed research informed consent 30 days before enrollment. 2. Pathologically confirmed positive pelvic lymph nodes (except total lymph node metastasis) Cervical cancer. 3. Aged 18 to 70 years; 4. Abdominal CT, MRI, or PET / CT found no retroperitoneal metastatic lymph nodes; 5. No evidence of distant metastasis; 6. ECOG score 0-2 or KPS score >=70; 7. The total blood cell count and basal metabolic index within 14 days before enrollment must meet the following requirements: NEUT >=1.5 * 10^9/L, HGB >=80 g/L, and blood creatinine <1.5 mg/dl; AST and ALT are within 2 times the upper limit of normal; 8. Assessments and examinations required before treatment must be completed before enrollment.
Exclusion criteria
Exclusion criteria: (1) There is metastasis to the total lymph nodes of the salamander; (2) Vaginal involvement is up to 1/3; (3) Involvement of bladder and rectal mucosa; (4) received cervical cancer radiotherapy or chemotherapy before treatment; (5) History of malignant tumors; (6) Previous medical history of abdominal or pelvic radiotherapy; (7) Women during pregnancy or lactation; (8) History of active inflammatory bowel disease, or severe gastric and duodenal ulcers; (9) With active infection and fever; (10) Those who are unable to tolerate concurrent chemoradiotherapy; (11) It is expected that internal radiation cannot be accepted; (12) History of severe lung or heart disease; (13) Circumstances in which other examiners determined from the enrollment study to be well-founded as failing: There were potential cases of non-compliance with the clinical protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Curative effect; | — |
Contacts
Public ContactFenghu Li
Affiliated Hospital of Guizhou Medical University/ Guizhou Cancer Hospital
Outcome results
None listed