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A randomized controlled trial for the association between restorative material and biologic complication related bacterial diversity on full-arch implant-supported restoration

The association between restorative material and biologic complication related bacterial diversity: a randomized controlled trial on full-arch implant-supported restoration

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000029470
Enrollment
Unknown
Registered
2020-02-02
Start date
2020-03-01
Completion date
Unknown
Last updated
2020-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

biologic complications on fixed full-arch implant-retained prosthesis

Interventions

Experimental group 1:zirconia prosthesis
Experimental group 2:acrylic resion

Sponsors

Peking University School and Hospitalof Stomatology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. edentulism; 2. general healthy,ASA I~II classification of American Society of Anesthesiologists; 3. aged over 18 years old; 4. good oral hygiene and good compliance; 5. sign an informed written consent form.

Exclusion criteria

Exclusion criteria: 1. poor oral hygiene and uncontrolled peridontitis; 2. antibiotics use for the past 3 months; 3. systemic disease: uncontrolled diabetes mellitus, cardiovascular disease, disease of immune system, blood disorders such as coagulation disorders, severe osteoporosis; 4. long-term medication users: steroid, anti-epileptic drug, biophosphonates; 5. HIV infection, Hepatitis B, syphilis; 6. bruxism; 7. smoker; 8. uncontrolled infection in the area intended for implant placement or other area; 9. maxillofacial tumor; 10. face-neck radiotherapy; 11. mental illness or high expectations.

Design outcomes

Primary

MeasureTime frame
PLI;PD;BI;microbiota;

Secondary

MeasureTime frame
subgingival inflammatory factors;

Countries

China

Contacts

Public ContactYang Jingwen

Stomatological Hospital of Beijing University

jingwen.yang@foxmail.com+86 15101157982

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 25, 2026