colorectal cancer
Conditions
Interventions
Experimental group 1:Combination of ultrasound-guided anterior quadratus lumborum block 2mg/kg and patient control intravenous analgesia
Experimental group 2:Combination of ultrasound-guided anterior quadratus lumborum block 3mg/kg and patient control intravenous analgesia
Sponsors
Department of Anesthesiology, the Second Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: This study was approved by the Research Ethics Committee of the Second Hospital of Shandong University ,all patients or authorized family members have signed informed consent. Seventy patients undergoing laparoscopic radical resection of colorectal cancer, aged more than 18 years old, body mass index between 18.5 and 28.0, ASA I-III, agreed to accept one of the three analgesic regimens randomly, were divided into three groups randomly.
Exclusion criteria
Exclusion criteria: History of anesthetic allergy, puncture site infection or trauma, hard to communicate, history of mental illness or recent use of psychotropic drugs, history of analgesic drug abuse, pregnancy, unclear anatomical structure shown by ultrasound, malformed vertebrae, severe organ dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analog scale, VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| plasma ropivacaine concentration; serum hs-TnI concentration;postoperative acute kidney injury indicator (creatinine, urea nitrogen);first anal exhaust time;overall benefit of analgesia;intraoperative sulfentanil consumption;intraoperative remifentanil consumption;intraoperative sevoflurane consumption;total number of postoperative PCA attempts;postoperative remedial analgesics usage;length of hospitalization;hospitalization expenses; | — |
Countries
China
Contacts
Public ContactYanwu Jin
The Second Hospital of Shandong University
Outcome results
None listed