dry eye
Conditions
Interventions
Health population:Nil
Sponsors
ZhuJiang Hospital of Southern Medicine University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for the control group subjects were an OSDI score 7 s, and Schirmer I test > 7 mm. All dry eye patients had experienced symptoms of dry eyes for more than one month and had an OSDI score > 12. Inclusion criteria in the dry eye group included either TBUT <=3 s, Schirmer <=5 mm/5 min, 3 s < TBUT <=10 s and positive fluorescein staining, or 5 mm/5 min < Schirmer <=10 mm/5 min and positive fluorescein staining.
Exclusion criteria
Exclusion criteria: 1) had active ocular infection or inflammation such as active allergic conjunctivitis, active trachoma, endophthalmitis, etc.; 2) had inflammation of the eyelid or the skin surrounding the eye, such as anterior blepharitis, etc.; 3) had eyelid abnormalities, such as eyelid varus, ectropion, eyelid tumor, eyelid insufficiency, severe trichiasis, severe ptosis, etc.; 4) had previous severe corneal damage, such as corneal chemical injuries, corneal dystrophy, etc.; 5) had other systemic diseases, such as Stevens-Johnson syndrome, graft versus host disease, vitamin A deficiency, Wegener's granulomatosis, Sjogrens syndrome, etc.; 6) had an allergy to sodium fluorescein; 7) used anti-inflammatory eye drops within one week prior to examination or artificial tears on the day of examination; 8) had a history of previous?ocular surgery within 3 months of examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| LT-alpha; | — |
Countries
China
Contacts
Public ContactXiaohe Lu
Department of Ophthalmology, Zhujiang Hospital, Southern Medical University
Outcome results
None listed