Gliomas
Conditions
Interventions
the 
imaging 
improve 
tumor 
rate 
and 
of 
Sponsors
Chinese Academy of Sciences, Institute of Automation
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) The patient himself voluntarily signs the informed consent form; (2) Patients aged 18 and 75 years male and female; (3) Patients with glioma and have been considered to be suitable for tumor resection surgery.(The grade given by enhanced MRI has no limitations.); (4) Patients with a KPS score higher than 70; (5) Patients with normal heart function; (6) Patients with normal bone marrow reserve function and liver and kidney function, which are determined by laboratory tests before surgery. The test items and criteria are as follows: absolute neutrophil >=1,500/mm3; hemoglobin >10 g/dL; platelet count >100,000/mm3; total bilirubin level < 1.5 ULN; alanine aminotransferase/glutagory aminotransferase < 2.5 ULN; serum creatinine < 1.5 ULN; (7) Patients who are compatible with follow-up; (8) Women of child-bearing age (15 to 49 years old) must undergo a pregnancy test within 7 days prior to initiation of treatment with negative results; male and female patients with fertility must agree to use effective contraceptive measures to ensure no pregnancy during the study period and within 3 months after discontinuation of treatment.
Exclusion criteria
Exclusion criteria: (1) Patients who cannot sign the informed consent form voluntarily; (2) Patients who are not suitable for glioma resection surgery; (3) Allergic patients; (4) Patients with any unstable systemic disease (including active infections, uncontrolled high blood pressure, unstable angina, angina pectoris that has started within the last 3 months, congestive heart failure, occurred within the first 12 months of enrollment Myocardial infarction, severe arrhythmia requiring medication, liver, kidney or metabolic disease); (5) Patients who are infected with human immunodeficiency virus (HIV) or with active hepatitis; (6) Patients who have participated in other clinical trials within the past 30 days; (7) Patients with mental illness, cognitive impairment, who are unable to understand the experimental scheme and side effects and to complete the experimental arrangements and follow-up(systematic assessment is required before enrolled in the trial); (8) Patients with no personal freedom and capacity for civil conduct.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| resection rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity; | — |
Countries
China
Contacts
Public ContactHu Zhenhua
Chinese Academy of Sciences, Institute of Automation
Outcome results
None listed