Nasopharyngeal Carcinoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 17 ~ 77 years; pathological diagnosis of WHO type II ~ III nasopharyngeal carcinoma; 2. The clinical stage is stage III ~ IVA; patients with nasopharyngeal carcinoma who need concurrent chemoradiotherapy; 3. Expected survival time is at least 6 months; 4. KPS score is greater than or equal to 70; 5. Sign the informed consent; 6. No history of severe heart disease and coronary heart disease; 7. Leukocyte count is greater than or equal to 4.0 x 10^9 / L, absolute neutrophil count is greater than or equal to 2.0 x 10^9 / L, platelet count is greater than or equal to 100 x 10^9 / L, and hemoglobin is greater than or equal to 80 g / L; 8. Total bilirubin, alanine aminotransferase and aspartate aminotransferase are all less than or equal to the upper limit; 9. Urine creatinine is less than or equal to the upper limit of normal value and creatinine clearance is 60 mL / min or more.
Exclusion criteria
Exclusion criteria: 1. Have a history of other malignant tumors; 2. Pregnant or lactating women; 3. Concomitant diseases or conditions affect the safety of patients during normal enrollment and study; 4. Existing active mental disorders or other mental illnesses that affect patients' signed informed consent and understanding; 5. Have severe active infections (including hepatitis); 6. Those who are allergic or sensitive to the test sample; 7. Patients with diabetes; 8. Investigators consider patients with poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival;Relapse-free survival; | — |
Countries
China
Contacts
Department of Oncology, Guigang City People's Hospital, the Eighth Affiliated Hospital of Guangxi Medical University