rotater cuff tear
Conditions
Interventions
1:bisphosphates (Alendronate)
2:no bisphosphates (blank control)
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Imaging confirmed that patients with full-thickness rotator cuff tear >= 3cm or involving two tendons. 2. Aged 18 ~ 75 years. 3. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with trauma or other shoulder joint diseases and malignant diseases. 2. History of shoulder joint neurological or muscular atrophy disease. 3. Unable to cooperate with the inspector. 4. Patients with other contraindications to surgery. 5. Endocrine diseases that affect bone metabolism: gonadal, thyroid gland, thyroid disease, etc.. 6. Long-term use of bisphosphates, glucocorticoids or other drugs that affect bone metabolism. 7. And various congenital and acquired bone metabolism disorders, etc..
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sugaya Classification of rotator cuff healing(integrity)/retear rate;UCLA score; | — |
Secondary
| Measure | Time frame |
|---|---|
| American Shoulder Elbow Surgeons Scale;Constant-Murley score;BMD;Osteocalcin;Bone Morphometric Evaluations of humeral head;Alkaline phosphatase;Parathyroid hormone;25-hydroxy-vitamin D;shoulder functional scores;VAS scores;range of motion;strength;fatty infiltration; | — |
Countries
China
Contacts
Public ContactJinzhong Zhao
Sports Medicine Department, Shanghai Sixth People's Hospital
Outcome results
None listed