Dry eye & MGD
Conditions
Interventions
Medication treatment group:pharmacological therapy (sodium hyaluronate with bromfenac sodium eye drops)
Combination therapy group:combination therapy (pharmacological therapy combined with meibomian gland massage)
Sponsors
Shenzhen Hospital, Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patient aged 18 to 80 years; 2. Diagnosed with glaucoma , and treated with anti-glaucoma eye drops for >=6 months; 3. Dry eye is identified according to the consensus of dry eye disease in China (2013): (1) at least 1 of 6 symptoms: dryness, gritty/sandiness, burning, tiredness, discomfort, and blurred vision with TFBUT (tear film break up time) 0; 4. Patients volunteered to participate and signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients have metabolic diseases, autoimmune diseases, connective tissue diseases and other systemic diseases, such as diabetes, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, Sjogren's syndrome, etc.; 2. Patients with major systemic diseases (including serious heart, cerebrovascular, liver and kidney and hematopoietic system, tumor and other diseases) and psychiatric patients; 3. Who had undergone dry eye treatment with lacrimal punctum embolism and surgery; 4. Have other eye diseases, such as eyelid defect, eyelid insufficiency, pterygium, chronic dacryocystitis, trichiasis, keratopathy, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ocular Surface Disease Index (OSDI) Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Corneal Staining scores;Schirmer I test(without anesthesia) score;tear break-up time (TFBUT);IOP score; | — |
Countries
China
Contacts
Public ContactYingli Li
Department of Ophthalmology, Shenzhen Hospital, Southern Medical University
Outcome results
None listed