Atrial Fibrillation
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Adults 40%; 6.Patients undergoing heart surgery for the first time; 7.Good compliance and ability to complete follow-up.
Exclusion criteria
Exclusion criteria: 1.History of AF; 2.Urgent or emergent cardiac surgery; 3.History of congenital heart diseases; 4.With mitral valve surgery; 5.Valve surgery is accompanied by other heart surgery; 6.Heart surgery is accompanied by surgery of other organ system; 7.Liver and kidney function abnormality (results exceed the upper limit of normal value by 3 times); 8.With valve surgery contraindications; 9.Patients suffer from other diseases who require radiotherapy, chemotherapy, and long-term hormone treatment; 10.Participated in other clinical trials; 11.Patients decline to consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of POAF (lasting more than 30 seconds) in both groups; | — |
Secondary
| Measure | Time frame |
|---|---|
| Days of hospital stay following surgery and ICU stay;Ventricular rate during AF;Inflammatory makers;Actionable AF: antiarrhythmic use (including rate-control meds), CDV, anticoagulation, use of inotropes for BP support during AF;Atrial fibrillation burden during the first week of operation;Number of episode > 24 hours, >48 hours;The incidence of Premature Atrial Contraction (PAC), Couplets and Nonsustained Atrial Tachyarrhythmia; | — |
Countries
China
Contacts
Department of Cardiovascular Surgery, General Hospital of Northern Theater Command