Atrial Fibrillation
Conditions
Sponsors
Department of Cardiovascular Surgery, General Hospital of Northern Theater Command
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Adults aged 18 to 80 years; 2. Patients with prior history of AF; 3. Non-urgent or non-emergent valve surgery; 4. With MI or AS, AI disease; 5. EF > 40%; 6. LAA > 50 mm; 7. Patients undergoing heart surgery for the first time; 8. Willing to paticipant in this trial and sign the informed consent, good compliance and ability to complete follow-up.
Exclusion criteria
Exclusion criteria: 1. With a history of adult congenital heart disease or valvular disease; 2. Have taken class I or III anti-arrhythmic drugs for any arrhythmia; 3. Valve surgery is accompanied by surgery of other heart surgery; 4. Heart surgery is accompanied by surgery of other organ system; 5. Liver and kidney function abnormality (results exceed the upper limit of normal value by 3 times); 6. With valve surgery contraindications; 7. Patients suffer from other diseases who require radiotherapy, chemotherapy, and long-term hormone treatment; 8. Participated in other clinical trials; 9. Patients decline to consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of POAF (lasting more than 30 seconds) in both groups; | — |
Secondary
| Measure | Time frame |
|---|---|
| Days of hospital stay following surgery;Ventricular rate during AF;Inflammatory makers;Actionable AF: antiarrhythmic use (including rate-control meds), CDV, anticoagulation, use of inotropes for BP support during AF;Atrial fibrillation burden during the first week of operation;Duration of Blocking time and extracorporeal circulation;The incidence of Premature Atrial Contraction (PAC), Couplets and Nonsustained Atrial Tachyarrhythmia;2D STI; | — |
Countries
China
Contacts
Public ContactHui-Shan Wang
Department of Cardiovascular Surgery, General Hospital of Northern Theater Command
Outcome results
None listed