Breast cancer
Conditions
Sponsors
Sun Yat-sen Memorial Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Sign the Informed Consent Form; 2. Pathologically diagnosed non-metastasis breast cancer,TNM stage II or above; 3. Pathologically diagnosed Luminal breast cancer by core needle biopsy; 4. Didn't receive chemotherapy,endocrinotherapy,breast cancer related surgery or radiotherapy historically; 5. UCG shows normal EF value; 6. ECGO scoring less than 2; 7. Suitable for chemotherapy.
Exclusion criteria
Exclusion criteria: 1. With other malignant apart from breast cancer, but skin basal cell carcinoma and carcinoma in situ of uterine cervix are excluded; 2. With active infection which is inappropriate for chemotherapy; 3. With other sever disease which is inappropriate for chemotherapy; 4. With mental illness which could not understand the Informed Consent Form; 5. With sever cardio dysfunction; 6. With sever liver dysfunction, ChildPugh C; 7. With sever renal dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pCR;RCB;Rate of breast conserving surgery;Adverse Event;the relationship between other biomarkers from blood and pCR;10-miRNA RS;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactErwei Song
Sun Yat-sen Memorial Hospital
Outcome results
None listed