critical limb ischemia
Conditions
Interventions
R:patient-control continuous sciatic block analgesia
I:patient-control intravenous morphine infusion
Sponsors
Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-80 years; 2. Diagnosed with critical limb ischemia, admitted in hospital for selective surgery treatment, either open surgical or endovascular revascularization; 3. The lesions are mainly unilateral and in the supplied area of sciatic nerve; 4. Stage 6 in Rutherford symptom classification system; 5. American Society of Anesthesiology (ASA) physical status II~III.
Exclusion criteria
Exclusion criteria: 1. Are taking opioids before admission; 2. Have known allergy to the drugs will be used in the study; 3. Have severe liver or kidney dysfunction; 4. Have contraindication for the catheterization (e.g. infection at injection site, coagulation disorders, refuse or be unable to cooperate the procedure); 5. The dorsum of the affected foot is not intact; 6. Are unable to understand the scales or to describe to the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| numerical rating scale (NRS); | — |
Secondary
| Measure | Time frame |
|---|---|
| transcutaneous oxygen pressure (TcPO2);tissue hemoglobin index (TOI);Hospital Anxiety and Depression Scale (HADS);Patient Global Impression of Change (PGIC);Cumulative morphine consumption perioperatively;Length of postoperative hospital stay;Adverse events (AEs);Patient satisfaction; | — |
Countries
China
Contacts
Public ContactSi Chen
Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College
Outcome results
None listed