HIV/HBV coinfection
Conditions
Interventions
Co-infected HIV/HBV cohort:Highly active antiretroviral therapy
HIV infected alone cohort:Highly active antiretroviral therapy
Sponsors
The Third People's Hospital of Shenzhen
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1)Age 18 to 70years old 2)No gender limitation 3)HIV-1/2 antibody was positive by ELISA and confirmed by Western Blot or HIV nucleic acid test 4)HBsAg positive was detected by ELISA 5)History of anti-HBV drug use is not limited 6)Sign the informed consent form voluntarily and guarantee the follow-up 7)There are no plans to relocate from the current study site during the course of the study 8)The researchers concluded that the overall condition of the subjects did not affect the evaluation and completion of the study
Exclusion criteria
Exclusion criteria: 1)Patients with opportunistic infection (stipulated by the national AIDS diagnosis and treatment guidelines) and unstable condition 2)Combined with malignant tumors other than liver cancer 3)With hepatitis C 4)Alcoholic hepatitis 5)With autoimmune hepatitis 6)With fatty liver disease 7)Drug user 8)Pregnant or lactating woman 9)With mental illness 10)Currently taking drugs that damage liver function 11)Non-chinese nationality
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fibroscan;Sound touch elastography;Fibrosis 4 Score;APRI;Liver biopsy; | — |
Countries
China
Contacts
Public ContactZhou Yang
The Third People's Hospital of Shenzhen
Outcome results
None listed