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Long-term follow-up outcomes of regarding the cumulative incidence of Hepatocellularhepatocellular carcinoma in among 362 patients with chronic hepatitis B without antiviral therapy

Long-term follow-up study of anti-inflammatory liver-protection and anti-viral on the incidence of liver cancer in patients with chronic hepatitis B

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000029281
Enrollment
Unknown
Registered
2020-01-20
Start date
2009-01-01
Completion date
Unknown
Last updated
2020-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic hepatitis B

Interventions

Case series:no

Sponsors

Shenzhen Traditional Chinese Medicine Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Chronic hepatitis B patients(no cirrhosis): (1) HBsAg positive for at least 6 months; (2) aged 18-75 years; (3) no interferon treatment; (4) Patients who just received Anti-inflammatory and liver-protecting therapy, ALT >=2 ULN, HBV DNA positive, follow-up time >=2 years; (5) anti-viral patients: voluntary nucleoside antiviral therapy, and follow-up time >=2 years, the time of Anti-inflammatory and liver-protecting treatment =7 points were diagnosed as decompensated for hepatitis B cirrhosis.

Exclusion criteria

Exclusion criteria: (1) patients with chronic hepatitis B complicated with drug-induced liver damage, alcoholic liver disease, autoimmune liver disease and other liver diseases; (2) patients with hepatocellular carcinoma; (3) liver cancer occurred within 1 year after treatment; (4) follow-up time of anti-inflammatory and liver-protecting patients less than 2 years; (5) follow-up time of anti-viral patients less than 2 years, anti-inflammatory and liver-protecting treatment time more than 6 months.

Design outcomes

Primary

MeasureTime frame
hcc;—

Countries

China

Contacts

Public ContactJiang Xiaoyan

Shenzhen Traditional Chinese Medicine Hospital

767463255@qq.com+86 13662291956

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026