The effect of Intensive therapy on subclinical synovitis of rheumatoid arthritis patients who have achieved treatment target -- a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000029279

Enrollment

Unknown

Registered

2020-01-20

Start date

2017-08-01

Completion date

Unknown

Last updated

2020-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid Arthritis

Interventions

A:maintenance therapy

B:intensive therapy

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1. Fulfill the 2010?ACR/EULAR RA classification; 2. Aged >=18 years old; 3. Achieved low disease activity or clinical remission; 4. The treatment strategy was stable for at least 12 weeks.

Exclusion criteria

Exclusion criteria: 1. Patients who have the complication of other rheumatic diseases; 2. Received steroid in the past 4 weeks; 3. Received NSAIDs in the past 1 week; 4. Patients with uncontrolled other chronic diseases, including asthma, Diabetes Mellitus, COPD, and severe interstitial lung disease; 5. Mental disorders; 6. Patents who are pregnant or plan to be pregnant in 2 years or nursing moms.

Design outcomes

Primary

Measure	Time frame
Joint ultrasound;C reactive protein;ESR;patients global assessment(PGA);evaluator global assessment (EGA);	—

Secondary

Measure	Time frame
Health Assessment Questionnaire disability index (HAQ-DI);rheumatoid factor(RF);	—

Countries

China

Contacts

Public ContactJuan Zhao

Peking University First Hospital

juanzi810819@163.com+86 13520966371

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 27, 2026