knee osteoarthritis
Conditions
Interventions
Experimental group:ultrasound guided intra-articular injection of PRP
Control group:ultrasound guided intra-articular injection of hyaluronic acid
Sponsors
Dept. of Rehabilitation Sciences, SunYat-Sen Memorial Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 70 Years
Inclusion criteria
Inclusion criteria: We recruited 50- to 70-year-old patients with knee OA based on ACR criteria who complained of relevant symptoms for at least 6 months. The diagnosis and grading of OA were made after obtaining knee x-ray in anteroposterior weight-bearing and lateral views.
Exclusion criteria
Exclusion criteria: (1) pyogenic arthritis of the knee; (2) recent severe knee trauma; (3) hip or ankle disease; (4) rheumatism and rheumatoid arthritis; (5) hematological diseases, such as hemophilia, platelet dysfunction; (6) serious cardiovascular disease, immune system disease; (7) hemoglobin lower than 12g/dL or platelet count It was lower than 150,000/uL; (8) anticoagulant or antiplatelet drugs were taken within 10 days before injection; (9) hormone was taken within 2 weeks before injection; (10) sodium hyaluronate injection, hormone or platelet rich plasma therapy had been taken in the knee joint cavity within the previous year; (11) Allergic to the drugs used in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC; | — |
Secondary
| Measure | Time frame |
|---|---|
| FSE T2WI;VAS;Quality of Life; | — |
Countries
China
Contacts
Public ContactLi Xiao
Dept. of Rehabilitation Sciences, Sun Yat-Sen Memorial Hospital
Outcome results
None listed