Effect of 6-aminocaproic acid on cleft palate repair in infants: a randomized, double-blind controlled study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000029252

Enrollment

Unknown

Registered

2020-01-20

Start date

2020-02-01

Completion date

Unknown

Last updated

2020-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cleft Palate

Interventions

Group A :6-aminocaproic acid was pumped intravenously

Group C:normal saline was pumped intravenously

Eligibility

Sex/Gender

All

Age

0.5 Years to 1 Years

Inclusion criteria

Inclusion criteria: Infants aged from 6 to 12 months, ASA I-II, scheduled for palate repair.

Exclusion criteria

Exclusion criteria: Complicated with diseases of the blood system, abnormal blood coagulation, oral anticoagulants, vitamin K deficiency, diseases of the liver and biliary system, difficult airway, allergy to aminohexic acid, complicated with severe cardiopulmonary diseases, postoperative ventilator support treatment for other reasons, epilepsy.

Design outcomes

Primary

Measure	Time frame
Wound bleeding score at extubation;	—

Secondary

Measure	Time frame
Surgical field bleeding score;amount of bleeding;Duration of the operation;Airway risk events during 24 hours after surgery;Ramsay score at extubation;Fibrinogen concentration at 24 hours after surgery;hospital stay;bleeding related additional surgery;	—

Countries

China

Contacts

Public ContactGaofeng Yu

Guangzhou Women and Children's Medical Center

76434960@qq.com+86 020 38076243

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026