knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) patients requiring unilateral initial TKA surgery ; (2) aged 50 to 80 years; (3) body mass index was 20~35 kg/m2; (4) the American Society of Anesthesiologists (ASA) classification (anesthesia risk assessment) is I ~ III level; (5) Understand and comply with the study protocol.
Exclusion criteria
Exclusion criteria: (1)surgical history of knee joint and surgical limb neuropathy; (2)alcohol or drug abuse and and allergic to any drugs in this trial,Contraindicated use of glucocorticoids; (3)long-term opioid users; (4)Inability to provide informed consent due to mental incompetence (e.g., intellectual disability, dementia); (5)local skin infection and bleeding at the puncture site of anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analog scale pain score at rest /activity;Timed up and go (TUG) test; | — |
Secondary
| Measure | Time frame |
|---|---|
| TTime of first dose of rescue analgesia;Opiod consumption after surgery;Quadriceps muscle strength; | — |
Countries
China
Contacts
Xi'an Honghui Hospital