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Study on Compositional and Functional Difference of Gut Microbiota between postmenopausal osteoporosis and Healthy Control Group.

Study on Compositional and Functional Difference of Gut Microbiota between postmenopausal osteoporosis and Healthy Control Group.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000029237
Enrollment
Unknown
Registered
2020-01-19
Start date
2020-01-09
Completion date
Unknown
Last updated
2022-04-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postmenopausal osteoporosis

Interventions

Postmenopausal osteoporosis:N/A
Postmenopausal osteopenia: N/A

Sponsors

Henan Pprovincial People Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
45 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 45 to 70 years; 2. Suspension for more than 1 year.

Exclusion criteria

Exclusion criteria: 1. Violent fractures caused by violence or trauma; 2. Suffered from other bone diseases, such as osteomalacia, renal osteodystrophy and other metabolic bone diseases or bone tumors; 3. Had acute or chronic inflammatory or infectious diseases, or who are being treated with antibiotics, probiotics, probiotics or any other medication that may affect the intestinal microbiota in the first three months of inclusion; 4. Had taken drugs that can cause osteoporosis, such as antidepressant; 5. Had serious organic diseases, such as cancer, coronary heart disease, myocardial infarction and stroke, etc; 6. Excessive drinking; 7. Anemia: hemoglobin < 10g/dl; 8. Had a physical disability or self-care disability or were unable to recall clearly and answer questions due to any other reasons; 9. Lacked the time to take part in this project.

Design outcomes

Primary

MeasureTime frame
Composition and functional characteristics of gut microbiota;

Secondary

MeasureTime frame
Bone mineral density and t value of lumbar spine and femoral neck;Composition and functional characteristics of vagina microbiota;Estrogen;Bone metabolism index;

Countries

China

Contacts

Public ContactHuijuan Yuan

Henan Pprovincial People Hospital

hjyuan@zzu.edu.cn+86 13513891997

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026